Description

Protein Kinase C B1 Peptide is a synthetic, biologically active peptide fragment corresponding to a specific sequence of the Protein Kinase C beta I (PKCβI) enzyme. This compound is a critical research tool for investigating the structure, function, and regulation of PKC isoforms, which are central to numerous cellular signaling pathways. It is primarily utilized by researchers and scientists in the fields of biochemistry, molecular biology, and pharmaceutical development for kinase assays, antibody production, and mechanistic studies related to cancer, cardiovascular diseases, and neurological disorders.

Application

• Biochemical Research: Used as a substrate or inhibitor in in vitro kinase activity assays to study PKCβI enzyme kinetics and regulation.
• Antibody Development: Serves as a key immunogen for generating and screening specific polyclonal or monoclonal antibodies against the PKCβI isoform.
• Signal Transduction Studies: Employed to probe intracellular signaling cascades, helping to elucidate the role of PKCβI in cell proliferation, differentiation, and apoptosis.
• Drug Discovery & Screening: Acts as a target molecule in high-throughput screening platforms to identify and validate novel PKC modulators for therapeutic development.
• Diagnostic Assay Development: Utilized in the development of ELISA or other immunoassays for detecting PKCβI levels or activity in research samples.
• Academic & Pharmaceutical R&D: A fundamental reagent for basic research and pre-clinical studies in universities, research institutes, and biopharmaceutical companies.

Basic Information

Product Name	Protein Kinase C B1 Peptide
CAS No.	155773-74-3
Molecular Formula	C84H138N24O23S
Molecular Weight	1884.2 g/mol
Synonyms	PKC βI Peptide; Protein Kinase C Beta I Peptide; PKCβI (206-226); PKCbetaI Peptide; PKC βI (206-226); PKC Pseudosubstrate Peptide; RFARKGSLRQKNV; V5 Region Peptide (PKC βI); PKC Inhibitory Peptide (19-31); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research-grade biochemicals. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and peptide content. Certificates of Analysis (COA) detailing specific results for HPLC purity, amino acid analysis, and mass spectrometry are available upon request to support your research documentation and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Amino Acid Composition	Within ±10% of theoretical
Solubility	Soluble in water or aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.