Description

Pegorgotein is a recombinant human superoxide dismutase (SOD) mimetic, a potent antioxidant enzyme engineered for therapeutic applications. This compound is critical for mitigating oxidative stress, a key factor in inflammatory and ischemic-reperfusion injury pathways. It is primarily utilized by pharmaceutical R&D teams and manufacturers developing advanced therapies for conditions such as stroke, myocardial infarction, and neurodegenerative diseases.

Application

• Pharmaceutical Research & Development: As a key active pharmaceutical ingredient (API) in preclinical and clinical studies for oxidative stress-related disorders.
• Neuroprotective Agent Development: For formulating therapies targeting stroke, traumatic brain injury, and conditions like Parkinson's or Alzheimer's disease.
• Cardiovascular Therapeutics: Used in research for drugs aimed at reducing damage from myocardial infarction and ischemia-reperfusion injury.
• Anti-inflammatory Formulations: Incorporated into biopharmaceuticals designed to control inflammatory responses in autoimmune diseases.
• Biochemical Research: Serves as a standard or tool compound in studies of free radical biology and antioxidant mechanisms.

Basic Information

Product Name	Pegorgotein
CAS No.	155773-57-2
Molecular Formula	C_{n}H_{m}N_{o}O_{p}S_{q} (Polyethylene glycol-conjugated protein)
Molecular Weight	~ 80,000 - 100,000 Da (PEGylated form)
Synonyms	PEG-SOD; Polyethylene Glycol-Conjugated Superoxide Dismutase; PEGylated Orgotein; Recombinant Human PEG-SOD; Superoxide Dismutase Mimetic PEG Conjugate; Oxidative Stress Therapeutic Agent; EC 1.15.1.1 (PEGylated); SOD-PEG
EINECS	Contact for details

Quality Control

Our Pegorgotein is manufactured under strict quality systems. Each batch is characterized for identity, purity, potency, and PEGylation ratio using advanced analytical techniques. We provide comprehensive Certificates of Analysis (COA) detailing specifications for research and cGMP-grade material, supporting regulatory filings for therapeutic development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (SDS-PAGE / SEC-HPLC)	≥ 95%
Protein Content (UV)	≥ 90% of theoretical
Specific Activity (Enzymatic Assay)	Reported per batch
PEGylation Ratio (MALDI-TOF)	Reported per batch
Endotoxin (LAL)	< 10 EU/mg
Residual Moisture (KF)	< 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.