Description

Ethyl 4-Oxo-4-(4-Trifluoromethylphenyl)Butyrate is a high-purity organic ester compound featuring a trifluoromethylphenyl ketone moiety, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for scale-up and production.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Organic Synthesis & Catalysis Research: A versatile substrate for Michael additions, aldol condensations, and other C-C bond-forming reactions in academic and industrial R&D settings.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions where required.

Basic Information

Product Name	Ethyl 4-Oxo-4-(4-Trifluoromethylphenyl)Butyrate
CAS No.	155722-95-5
Molecular Formula	C₁₃H₁₃F₃O₃
Molecular Weight	274.24 g/mol
Synonyms	Ethyl 4-(4-Trifluoromethylbenzoyl)butyrate; 4-Oxo-4-[4-(trifluoromethyl)phenyl]butanoic Acid Ethyl Ester; Ethyl 4-(4-Trifluoromethylbenzoyl)butanoate; Butanoic acid, 4-oxo-4-[4-(trifluoromethyl)phenyl]-, ethyl ester; Ethyl γ-Oxo-4-(trifluoromethyl)benzenebutanoate; 155722-95-5; 4-(4-Trifluoromethylphenyl)-4-oxobutyric acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 4-Oxo-4-(4-Trifluoromethylphenyl)Butyrate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the stringent requirements for advanced intermediate applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as identity, purity, and impurity profile. Our quality commitment supports compliance with relevant guidelines for pharmaceutical and agrochemical ingredient sourcing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.