Description

Minodronic Acid is a potent third-generation bisphosphonate compound, recognized for its high affinity for bone hydroxyapatite. This compound is a critical active pharmaceutical ingredient (API) valued for its efficacy in modulating bone metabolism. It is primarily utilized in the pharmaceutical industry for the development and manufacturing of treatments for bone-related disorders such as osteoporosis and Paget's disease. Our supply ensures high purity and consistent quality for reliable research and production outcomes.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for osteoporosis and other metabolic bone diseases.
• Research & Development: Serves as a key reference standard and building block in pharmacological and biochemical research focused on bone biology.
• Formulation Development: Used in the development of various dosage forms, including tablets and injectables, requiring precise API quality.
• Clinical Trial Material: Supplied as a high-purity compound for use in clinical studies evaluating new therapeutic regimens.
• Comparative Studies: Employed in analytical laboratories for method development and impurity profiling against other bisphosphonates.

Basic Information

Product Name	Minodronic Acid
CAS No.	155648-60-5
Molecular Formula	C9H12N2O7P2
Molecular Weight	322.15 g/mol
Synonyms	Minodronic Acid; YM-529; Minodronate; (1-Hydroxy-2-imidazo[1,2-a]pyridin-3-ylethane-1,1-diyl)bis(phosphonic acid); ONO-5920; Minodronic Acid Monohydrate; Minodronate Monohydrate; Minodronic Acid Hydrate
EINECS	Contact for details

Quality Control

Our Minodronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider desiccants or an inert atmosphere to maintain stability and prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.