Description

1-Benzyl-3-Boc-Aminomethylpyrrolidine is a high-purity, protected amine building block of significant importance in modern organic synthesis. Its core value lies in providing a versatile and reactive scaffold for constructing complex nitrogen-containing molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as medicinal chemistry and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization due to its protected amine functionality.
• Peptidomimetic Synthesis: Serves as a constrained proline-like scaffold for creating peptide analogs with enhanced metabolic stability.
• Agrochemical Research: Employed in the development of new pesticides and herbicides that require complex amine architectures.
• Ligand and Catalyst Development: Useful for constructing chiral ligands for asymmetric catalysis.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke fine chemicals.

Basic Information

Item	Details
Product Name	1-Benzyl-3-Boc-Aminomethylpyrrolidine
CAS No.	155497-10-2
Molecular Formula	C18H28N2O2
Molecular Weight	304.43 g/mol
Synonyms	1-Benzyl-3-[(tert-butoxycarbonyl)aminomethyl]pyrrolidine; tert-Butyl N-[[1-benzylpyrrolidin-3-yl]methyl]carbamate; 3-(Boc-aminomethyl)-1-benzylpyrrolidine; 1-Benzyl-3-(Boc-aminomethyl)pyrrolidine; N-Boc-3-aminomethyl-1-benzylpyrrolidine; (1-Benzylpyrrolidin-3-yl)methyl tert-butylcarbamate; 155497-10-2; Boc-AMBnP
EINECS	Contact for details

Quality Control

Our 1-Benzyl-3-Boc-Aminomethylpyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable consistency and traceability for your research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.