Description

1,2,3,4-Tetra-o-Acetyl-6-Deoxy-6-Fluoro-D-Galactopyranose is a key fluorinated carbohydrate intermediate, specifically a peracetylated galactose derivative where the 6-hydroxyl group is replaced by fluorine. This chemical modification is crucial for imparting metabolic stability and altering biological activity in final compounds. It is primarily utilized by pharmaceutical and biotechnology research organizations for the synthesis of novel fluorinated nucleosides, glycoconjugates, and diagnostic probes.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of fluorinated antiviral and anticancer nucleoside analogs.
• Glycobiology Research: Used in the preparation of stable fluorinated sugar analogs to study enzyme mechanisms and carbohydrate-protein interactions.
• Diagnostic Agent Development: Serves as a precursor for Positron Emission Tomography (PET) tracers, particularly those labeled with fluorine-18 (18F).
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies by introducing a fluorine atom at the 6-position of galactose scaffolds.
• Chemical Biology Probes: Facilitates the creation of metabolic inhibitors and activity-based probes for glycosidases and glycosyltransferases.

Basic Information

Product Name	1,2,3,4-Tetra-o-Acetyl-6-Deoxy-6-Fluoro-D-Galactopyranose
CAS No.	155488-15-6
Molecular Formula	C14H19FO9
Molecular Weight	350.29 g/mol
Synonyms	6-Deoxy-6-fluoro-1,2,3,4-tetra-O-acetyl-α/β-D-galactopyranose; 6-Fluoro-1,2,3,4-tetra-O-acetyl-D-galactose; 6-Fluoro-D-galactose tetraacetate; 1,2,3,4-Tetra-O-acetyl-6-deoxy-6-fluoro-D-galactose; 6-Fluoro-1,2,3,4-tetra-O-acetyl-α-D-galactopyranose; 6-Fluoro-1,2,3,4-tetra-O-acetyl-β-D-galactopyranose; Tetra-O-acetyl-6-fluoro-D-galactopyranose
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetra-o-Acetyl-6-Deoxy-6-Fluoro-D-Galactopyranose is manufactured under strict quality systems to ensure batch-to-batch consistency for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.