Description

4-Benzyl-3-Pent-4-Enoyl-1,3-Oxazolidin-2-One is a high-value, specialized chiral auxiliary and synthetic intermediate. This compound is critical for enabling highly stereoselective transformations in complex organic synthesis, particularly in the construction of natural products and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over molecular architecture.

Application

• Asymmetric Synthesis: A key chiral auxiliary for aldol, alkylation, and Diels-Alder reactions to install stereocenters with high enantiomeric excess.
• Pharmaceutical Intermediates: Critical building block in the synthesis of complex drug candidates, including potential antiviral and anti-inflammatory agents.
• Agrochemical Development: Used in the research and production of enantiomerically pure pesticides and herbicides.
• Natural Product Synthesis: Facilitates the stereocontrolled construction of complex natural products for research and development.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable synthetic routes for commercial manufacturing.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and new reaction development.

Basic Information

Product Name	4-Benzyl-3-Pent-4-Enoyl-1,3-Oxazolidin-2-One
CAS No.	155399-10-3
Molecular Formula	C₁₅H₁₇NO₃
Molecular Weight	259.30 g/mol
Synonyms	(S)-4-Benzyl-3-(pent-4-enoyl)oxazolidin-2-one; (S)-4-Benzyl-3-(4-pentenoyl)-2-oxazolidinone; Evans Auxiliary derivative; N-(4-Pentenoyl)-4-benzyl-2-oxazolidinone; (S)-N-Pent-4-enoyl-4-benzyl-2-oxazolidinone; (S)-4-Benzyl-3-(pent-4-enoyl)oxazolidin-2-one; (S)-3-(4-Pentenoyl)-4-benzyl-2-oxazolidinone
EINECS	Contact for details

Quality Control

Our 4-Benzyl-3-Pent-4-Enoyl-1,3-Oxazolidin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.