Description

Hemoglobin Sinai-Baltimore is a specialized variant of hemoglobin, a critical oxygen-transporting metalloprotein found in red blood cells. This specific variant is of significant interest in biochemical research and diagnostic development due to its unique structural and functional properties. It is primarily utilized by research institutions, pharmaceutical developers, and clinical diagnostic manufacturers for advanced studies in hematology, genetic disorders, and the development of reference standards.

Application

• Biochemical Research: Used as a key reagent in studies investigating hemoglobin structure-function relationships, oxygen affinity, and allosteric regulation.
• Diagnostic Development: Serves as a critical component or calibrator in the development of in-vitro diagnostic (IVD) assays for detecting hemoglobinopathies and blood disorders.
• Pharmaceutical Reference Standard: Employed as a high-purity reference material for quality control and method validation in biopharmaceutical processes.
• Hematology Studies: Applied in laboratory investigations of sickle cell disease, thalassemia, and other genetic variations affecting hemoglobin.
• Educational & Clinical Training: Used in academic and clinical settings for teaching and training purposes related to clinical chemistry and molecular pathology.

Basic Information

Product Name	Hemoglobin Sinai-Baltimore
CAS No.	155328-29-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb Sinai-Baltimore; Hemoglobin variant Sinai-Baltimore; Hb S-Baltimore; Hemoglobin S-B; Hemoglobin mutant Sinai-Baltimore; Abnormal hemoglobin Sinai-Baltimore; Globin variant Sinai-Baltimore
EINECS	Contact for details

Quality Control

Our Hemoglobin Sinai-Baltimore is produced and handled under stringent quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and stability, meeting the exacting standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identification, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Dark red to brown lyophilized powder or solution
Identification (IR / HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95% (or as per customer grade requirement)
Protein Content (Biuret / UV-Vis)	Reported on COA
Solubility	Clear solution in appropriate buffer
Moisture Content (Karl Fischer)	≤ 5.0% (for lyophilized form)
Biological Activity (Oxygen Binding)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.