Description

Ethyl 2-Fluorocyclopropanecarboxylate is a versatile fluorinated cyclopropane derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique strained-ring structure combined with a fluorine substituent makes it a valuable precursor for introducing conformational rigidity and modulating electronic properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, including protease inhibitors, CNS-active compounds, and antiviral agents.
• Agrochemical Synthesis: Building block for novel pesticides and herbicides, where the fluorocyclopropane moiety can enhance biological activity and environmental stability.
• Material Science Research: Used in the synthesis of specialty monomers and polymers with tailored properties for advanced materials.
• Asymmetric Synthesis: Chiral template for constructing complex, enantiomerically pure molecules in medicinal chemistry and catalysis research.
• Fluorine Chemistry Studies: A model compound for investigating the reactivity and stereoelectronic effects of fluorinated three-membered rings.
• Ligand and Catalyst Development: Precursor for creating novel chiral ligands and organocatalysts used in stereoselective transformations.

Basic Information

Product Name	Ethyl 2-Fluorocyclopropanecarboxylate
CAS No.	155051-95-9
Molecular Formula	C6H9FO2
Molecular Weight	132.13 g/mol
Synonyms	2-Fluorocyclopropanecarboxylic Acid Ethyl Ester; Ethyl 2-Fluorocyclopropane-1-carboxylate; 1-Carbethoxy-2-fluorocyclopropane; Ethyl 2-Fluorocyclopropanecarboxylate; 2-Fluorocyclopropanecarboxylic Acid Ethyl Ester; 155051-95-9; Ethyl 2-fluorocyclopropanecarboxylate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-Fluorocyclopropanecarboxylate is produced and tested under strict quality management protocols to ensure consistency and purity for research and scale-up applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to meet the stringent requirements of advanced synthetic chemistry. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use and stored away from heat sources and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Specific Rotation (if chiral)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.