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4-Fluorobenzyltrozamicol CAS NO 154824-77-8


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CAS No.:154824-77-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Fluorobenzyltrozamicol is a high-purity chemical intermediate of significant interest in advanced pharmaceutical research and development. Its primary value lies in its role as a key building block for synthesizing novel compounds targeting specific neurological pathways. This product is essential for research institutions and pharmaceutical companies engaged in the development of diagnostic agents and therapeutic candidates for central nervous system disorders. We supply this material with a focus on batch-to-batch consistency and reliable global logistics to support critical R&D timelines.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of advanced radiopharmaceuticals and positron emission tomography (PET) tracers.
  • Neurological Research: Used in the development of ligands for studying the vesicular acetylcholine transporter (VAChT) system.
  • Diagnostic Agent Development: Serves as a key scaffold for creating compounds used in neuroimaging to assess conditions like Alzheimer's disease and Parkinson's disease.
  • Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize potency and selectivity of candidate drug molecules.
  • Reference Standard: Can be utilized as an analytical standard in quality control laboratories for method development and validation.
  • Preclinical Studies: Supports in vitro and in vivo research to evaluate the biodistribution and pharmacokinetics of novel therapeutic agents.

Basic Information

Product Name 4-Fluorobenzyltrozamicol
CAS No. 154824-77-8
Molecular Formula C20H21FN2O
Molecular Weight 324.40 g/mol
Synonyms 4-Fluorobenzyltrozamicol; (1R,2R)-4-(4-Fluorobenzyl)-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolin-9-ol; (-)-4-(4-Fluorobenzyl)trozamicol; 4-FBT; Trozamicol, 4-(4-fluorobenzyl)-, (1R,2R)-rel-; VAChT Ligand precursor
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Quality Control

Every batch of 4-Fluorobenzyltrozamicol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as identity, purity, and impurity profile. Our quality commitment supports compliance with relevant guidelines for advanced intermediates used in drug discovery and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC) Complies with ICH guidelines
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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