Description

Acetamide, 2,2,2-Trifluoro-n-(1-α-,3-Ba-,5-α-)-6-Oxabicyclo[3.1.0]Hex-3-Yl- (9Ci) is a specialized fluorinated acetamide derivative featuring a complex oxabicyclo[3.1.0]hexane scaffold. This compound is valued for its unique structural framework, which combines a trifluoroacetamide moiety with a constrained, bridged bicyclic ether system, making it a high-value chemical intermediate for advanced research and synthesis. It is primarily sought by pharmaceutical and agrochemical research organizations for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability.
• Agrochemical Research: Used in the discovery and development of new-generation herbicides, fungicides, or insecticides, where the oxabicyclo structure can impart unique biological activity.
• Advanced Material Synthesis: Acts as a precursor for specialty polymers or liquid crystals, where the rigid bicyclic core can influence material properties.
• Organic Synthesis & Method Development: Employed as a challenging substrate in academic and industrial laboratories for developing new fluorination or ring-opening reactions.
• Ligand & Catalyst Development: The structure can be functionalized to create novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-(1-α-,3-Ba-,5-α-)-6-Oxabicyclo[3.1.0]Hex-3-Yl- (9Ci)
CAS No.	154705-97-2
Molecular Formula	C9H10F3NO2
Molecular Weight	221.18 g/mol
Synonyms	2,2,2-Trifluoro-N-[(1R,3S,5R)-6-oxabicyclo[3.1.0]hex-3-yl]acetamide; N-[(1α,3β,5α)-6-Oxabicyclo[3.1.0]hex-3-yl]-2,2,2-trifluoroacetamide; Trifluoroacetamide oxabicyclohexane derivative; (1R,3S,5R)-6-Oxabicyclo[3.1.0]hexan-3-amine, N-(trifluoroacetyl)-; 154705-97-2; 6-Oxabicyclo[3.1.0]hex-3-ylamine, N-(trifluoroacetyl)-, (1α,3β,5α)-
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, GC, NMR, and MS, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key specifications. Our manufacturing processes adhere to ISO 9001 standards, and we can support development projects requiring compliance with GMP or ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.