Description

Deacetyltaxol C, 10-(Rg) is a high-purity, semi-synthetic taxane derivative, a key intermediate in the synthesis of complex pharmaceutical compounds. Its value lies in providing a structurally defined and reliable building block for advanced research and development in medicinal chemistry. This product is essential for pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on oncology drug discovery and the synthesis of novel taxane-based therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent anti-cancer agents and other bioactive taxane molecules.
• Medicinal Chemistry Research: Used as a scaffold or starting material for structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Reference Standard: Serves as an analytical standard for quality control and method development in HPLC and LC-MS analysis of taxane mixtures.
• Process Chemistry Development: Employed in optimizing synthetic routes and scaling up production for novel pharmaceutical actives.
• Biochemical Research: Used in studies investigating tubulin polymerization dynamics and the mechanism of action of taxane derivatives.

Basic Information

Product Name	Deacetyltaxol C, 10-(Rg)
CAS No.	154677-95-9
Molecular Formula	C45H49NO13
Molecular Weight	811.88 g/mol
Synonyms	10-Deacetyl-10-oxo-7-epitaxol; 10-Deacetyl-10-oxo-7-epi-paclitaxel; 7-Epi-10-deacetyl-10-oxotaxol; 10-Oxo-7-epitaxol; 10-Deacetyl-10-oxo-7-epitaxol C; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecah-6,11-dihydroxy-4a,8,13,13-tetramethyl-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate
EINECS	Contact for details

Quality Control

Our Deacetyltaxol C, 10-(Rg) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.