Description

2-(2-Fluorophenyl)-6,7-Methylenedioxy-2-4-Quinolone Hydrate, NSC 656158 is a specialized fluorinated quinolone derivative, a high-value building block in advanced organic synthesis. This compound is critical for research and development in medicinal chemistry, particularly for creating novel pharmacologically active molecules. It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers developing new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential new drug candidates, especially those targeting kinase inhibition or other enzyme-related pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Agrochemical Development: Employed in the research phase for creating new herbicides or fungicides, leveraging the bioactivity of the quinolone structure.
• Biochemical Tool Compound: Acts as a reference standard or probe molecule in biochemical assays to study specific biological mechanisms.
• Fine Chemical Synthesis: Utilized in multi-step synthetic routes to produce complex, fluorinated organic molecules for various high-tech applications.

Basic Information

Product Name	2-(2-Fluorophenyl)-6,7-Methylenedioxy-2-4-Quinolone Hydrate, NSC 656158
CAS No.	154554-41-3
Molecular Formula	C₁₇H₁₂FNO₄ • xH₂O
Molecular Weight	313.28 g/mol (Anhydrous basis)
Synonyms	NSC 656158; NSC-656158; 2-(2-Fluorophenyl)-6,7-methylenedioxyquinolin-4(1H)-one hydrate; 2-(2-Fluorophenyl)-6,7-(methylenedioxy)-4(1H)-quinolinone hydrate; 4-Quinolinone, 2-(2-fluorophenyl)-6,7-(methylenedioxy)-, hydrate (1:?); 154554-41-3 (Parent CAS)
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Fluorophenyl)-6,7-Methylenedioxy-2-4-Quinolone Hydrate is produced and tested under strict quality management protocols. We ensure identity, purity, and consistency through advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.