Description

2-Furanaceticacid,4-Fluoro-2,5-Dihydro-5-Oxo-,(2R)-(9Ci) is a high-purity chiral building block and advanced pharmaceutical intermediate of significant synthetic value. This compound is critical for research and development in medicinal chemistry, particularly for constructing complex molecules with defined stereochemistry. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and for the synthesis of complex heterocyclic libraries for biological screening.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to introduce the (2R) stereocenter into target molecules.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value fluorinated compounds.
• Academic & Institutional R&D: Utilized in university and government laboratories for fundamental research in organic synthesis and methodology development.

Basic Information

Product Name	2-Furanaceticacid,4-Fluoro-2,5-Dihydro-5-Oxo-,(2R)-(9Ci)
CAS No.	154540-22-4
Molecular Formula	C6H5FO4
Molecular Weight	160.10 g/mol
Synonyms	(2R)-4-Fluoro-2,5-dihydro-5-oxo-2-furanacetic acid; (R)-4-Fluoro-5-oxo-2,5-dihydrofuran-2-acetic acid; 4-Fluoro-5-oxo-2,5-dihydrofuran-2-acetic acid, (R)-; (R)-4-Fluoro-2,5-dihydro-5-oxofuran-2-acetic acid; (2R)-4-Fluoro-5-oxo-2,5-dihydrofuran-2-ylacetic acid; 154540-22-4; (R)-enantiomer of 4-Fluoro-5-oxo-2,5-dihydrofuran-2-acetic acid
EINECS	Contact for details

Quality Control

Our 2-Furanaceticacid,4-Fluoro-2,5-Dihydro-5-Oxo-,(2R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.