Description

1 3-Bis(tert-Butoxycarbonyl)Guanidine is a high-purity, protected guanidine derivative widely used as a key synthetic intermediate in organic and medicinal chemistry. Its primary value lies in its role as a versatile building block for introducing the guanidine functional group under mild conditions, enabling the synthesis of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of guanidine-containing drug candidates, including protease inhibitors, antiviral agents, and cardiovascular drugs.
• Peptide Mimetics & Modifications: Used to introduce guanidine groups into peptide backbones to enhance binding affinity, stability, and bioavailability.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and plant growth regulators with guanidine motifs.
• Material Science Research: Employed in the development of functional polymers, dendrimers, and supramolecular structures that utilize guanidine's hydrogen-bonding capabilities.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study enzyme mechanisms and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis services targeting complex, multi-step organic transformations.

Basic Information

Item	Details
Product Name	1 3-Bis(tert-Butoxycarbonyl)Guanidine
CAS No.	154476-57-0
Molecular Formula	C₁₁H₂₁N₃O₄
Molecular Weight	259.30 g/mol
Synonyms	1,3-Di-Boc-guanidine; N,N'-Di-Boc-guanidine; 1,3-Bis[(tert-butoxy)carbonyl]guanidine; Di-tert-butyl 1,3-diguanidino-2,4-diazabutane-1,3-dicarboxylate; Guanidine, N,N'-bis(1,1-dimethylethyl) ester; Boc-Guanidine-Boc; BOC-GUA(BOC)-OH (protected form); (tert-Butoxycarbonyl)guanidine derivative
EINECS	Contact for details

Quality Control

Our 1 3-Bis(tert-Butoxycarbonyl)Guanidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our production adheres to cGMP guidelines where applicable, ensuring consistency and reliability for your research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions, preferably in a nitrogen atmosphere, to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.