Description

3'-Bromo-5'-(trifluoromethyl)acetophenone, 97% is a high-purity, multi-functional organic building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for facilitating advanced molecular synthesis, offering chemists a versatile handle for cross-coupling reactions and the introduction of fluorine-containing motifs. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules for drug discovery and development, particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to construct complex biaryl structures.
• Fluorine Chemistry Studies: An important reagent for investigating the effects of fluorine substitution on the physicochemical properties of organic compounds.
• Chemical Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development and quality control.

Basic Information

Product Name	3'-Bromo-5'-(trifluoromethyl)acetophenone, 97%
CAS No.	154259-25-3
Molecular Formula	C9H6BrF3O
Molecular Weight	267.05 g/mol
Synonyms	1-(3-Bromo-5-(trifluoromethyl)phenyl)ethan-1-one; 3'-Bromo-α,α,α-trifluoro-m-acetophenone; 3-Bromo-5-(trifluoromethyl)acetophenone; 1-Acetyl-3-bromo-5-(trifluoromethyl)benzene; m-Bromo-α,α,α-trifluoroacetophenone; 3-Bromo-α,α,α-trifluoroacetophenone; 3-Bromo-5-trifluoromethylacetophenone
EINECS	Contact for details

Quality Control

Our 3'-Bromo-5'-(trifluoromethyl)acetophenone, 97% is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency meet the specified standards. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes for your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.