Description

[2-Cyclopropyl-4-(4-Fluorophenyl)-Quinolin-3-Ylmethyl]-Triphenyl-Phosphonium Bromido is a specialized organophosphonium salt with a complex heterocyclic structure, serving as a critical intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in pharmaceutical, agrochemical, and advanced material science sectors, where it facilitates the creation of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its unique fluorinated quinoline scaffold.
• Catalyst Ligand Synthesis: Serves as a precursor for phosphine-based ligands used in transition metal catalysis for cross-coupling reactions.
• Material Science: Building block for creating organic semiconductors and photoactive materials for electronic applications.
• Chemical Biology Probes: Utilized in the design of fluorescent tags and molecular probes for cellular imaging and diagnostic applications.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for complex organic molecules in pilot plant and manufacturing settings.

Basic Information

Product Name	[2-Cyclopropyl-4-(4-Fluorophenyl)-Quinolin-3-Ylmethyl]-Triphenyl-Phosphonium Bromido
CAS No.	154057-58-6
Molecular Formula	C₃₉H₃₂BrFNP
Molecular Weight	620.55 g/mol
Synonyms	Triphenyl[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinylmethyl]phosphonium bromide; (2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)methyltriphenylphosphonium bromide; 3-Quinolinemethanol, 2-cyclopropyl-4-(4-fluorophenyl)-, triphenylphosphonium bromide; Phosphonium, triphenyl[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinylmethyl]-, bromide; 154057-58-6; [2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinylmethyl]triphenylphosphonium bromide
EINECS	Contact for details

Quality Control

Our production of [2-Cyclopropyl-4-(4-Fluorophenyl)-Quinolin-3-Ylmethyl]-Triphenyl-Phosphonium Bromido adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.