Description

Ac-Dl-Phe(3,4-Cl2)-Oet CAS NO 153828-98-9 is a synthetic, non-natural amino acid derivative featuring a dichlorinated phenylalanine side chain, protected at the N-terminus with an acetyl group and esterified at the C-terminus. This specific chemical architecture makes it a valuable protected building block and key intermediate in advanced organic synthesis. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceutical candidates, peptidomimetics, and specialized fine chemicals.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic Design: Used to incorporate modified, chlorinated phenylalanine analogs into peptide chains to study structure-activity relationships (SAR) and enhance metabolic stability.
• Chemical Biology & Proteomics: Acts as a building block for creating custom peptides and molecular probes used in biochemical assays and target identification.
• Organic Synthesis Intermediate: Employed in multi-step synthetic routes for constructing complex molecules in medicinal and process chemistry.
• Academic Research: Utilized in university and institutional labs for methodological studies in peptide coupling and protecting group chemistry.

Basic Information

Product Name	Ac-Dl-Phe(3,4-Cl2)-Oet
CAS No.	153828-98-9
Molecular Formula	C13H15Cl2NO3
Molecular Weight	304.17 g/mol
Synonyms	N-Acetyl-3,4-dichloro-DL-phenylalanine ethyl ester; Ac-DL-Phe(3,4-diCl)-OEt; Ethyl N-acetyl-3,4-dichlorophenylalaninate; N-Acetyl-3,4-dichloro-DL-phenylalanine ethyl ester; Ac-3,4-Dichloro-DL-Phe-OEt; DL-N-Acetyl-3,4-dichlorophenylalanine ethyl ester; (RS)-2-Acetamido-3-(3,4-dichlorophenyl)propanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ac-Dl-Phe(3,4-Cl2)-Oet is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request. We adhere to industry-standard practices suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.