Description

Boc-Beta,β-Dimethyl-D-Cys(Npys)-Oh is a specialized, high-purity protected amino acid derivative used in advanced peptide synthesis. This compound matters for its role as a key building block in the production of complex peptides and peptidomimetics, offering precise control over stereochemistry and side-chain reactivity. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require reliable, high-quality intermediates for drug discovery and development.

Application

• Solid-Phase Peptide Synthesis (SPPS): A critical building block for the controlled introduction of the protected, activated cysteine derivative into peptide chains.
• Peptidomimetic Drug Development: Used to create synthetic analogs of natural peptides with enhanced stability and bioavailability for therapeutic applications.
• Conjugation Chemistry: The Npys (3-nitro-2-pyridinesulfenyl) protecting group allows for selective deprotection and subsequent formation of disulfide bonds or conjugation with other molecules.
• Research & Development: Serves as a valuable intermediate in academic and industrial R&D for studying protein-protein interactions and designing novel bioactive compounds.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	Boc-Beta,β-Dimethyl-D-Cys(Npys)-Oh
CAS No.	153815-23-7
Molecular Formula	C15H21N3O5S2
Molecular Weight	387.47 g/mol
Synonyms	Boc-D-Cys(Npys)-OH, beta,β-dimethyl; (R)-2-((tert-Butoxycarbonyl)amino)-3,3-dimethyl-4-((3-nitro-2-pyridyl)disulfanyl)butanoic acid; tert-Butyloxycarbonyl-D-beta,β-dimethylcysteine(Npys); Boc-D-beta,β-dimethylcysteine(Npys)-OH; Boc-D-Cys(Me)2(Npys)-OH; N-(tert-Butoxycarbonyl)-3,3-dimethyl-D-cysteine(Npys); Nα-Boc-D-β,β-dimethylcysteine(Npys) acid; Protected D-cysteine derivative
EINECS	Contact for details

Quality Control

Our Boc-Beta,β-Dimethyl-D-Cys(Npys)-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and cGMP applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed container to reach room temperature before opening to minimize condensation and exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.