Description

Propionic Acid (13C3) is a stable isotope-labeled analog of propionic acid, where all three carbon atoms are the carbon-13 isotope. This compound is an essential tool for advanced analytical research, providing a critical internal standard for precise quantification and metabolic pathway tracing using mass spectrometry and NMR spectroscopy. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, agrochemical, and life science sectors for method development, validation, and complex biochemical studies.

Application

• Internal Standard for Quantitative Analysis: Used in GC-MS and LC-MS methods for the accurate measurement of propionic acid and related metabolites in complex biological and environmental matrices.
• Metabolic Pathway Tracing: Enables the study of fatty acid metabolism, gut microbiome activity, and other biochemical processes in nutritional and medical research.
• Pharmaceutical Impurity Profiling: Serves as a reference standard in the identification and quantification of impurities and degradants in drug substances and products.
• Food and Feed Safety Analysis: Applied in methods to monitor preservative levels, study fermentation processes, and ensure regulatory compliance.
• Environmental Monitoring: Assists in tracking the fate and biodegradation of organic acids in ecological studies.
• NMR Spectroscopy: Acts as a chemical shift reference or a labeled precursor in synthetic chemistry for structural elucidation.

Basic Information

Product Name	Propionic Acid (13C3)
CAS No.	153474-35-2
Molecular Formula	13C3H6O2
Molecular Weight	77.05 g/mol
Synonyms	Propanoic-13C3 acid; [13C3]-Propionic Acid; 1,2,3-13C3-Propanoic Acid; Carbon-13 Labeled Propionic Acid; Ethanecarboxylic-13C3 acid; Methylacetic-13C3 acid; Metacetonic-13C3 acid; Propionic-13C3 Acid
EINECS	Contact for details

Quality Control

Our Propionic Acid (13C3) is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >99 atom % 13C), chemical purity (by HPLC/GC), and identity confirmation (by NMR and MS). We support compliance with cGMP guidelines for use as a reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep the container tightly sealed in a dry, well-ventilated place, away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.