Description

7-Fluorobenzoxazole-2(3H)-Thione is a high-value fluorinated heterocyclic building block with significant synthetic utility. This compound is prized for its role as a versatile intermediate in the development of advanced pharmaceuticals and agrochemicals. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with tailored biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Precursor: Serves as a building block for advanced organic materials, including ligands for catalysis and monomers for specialty polymers.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a core scaffold in fragment-based drug discovery.

Basic Information

Product Name	7-Fluorobenzoxazole-2(3H)-Thione
CAS No.	153403-54-4
Molecular Formula	C7H4FNOS
Molecular Weight	169.18 g/mol
Synonyms	7-Fluoro-2-benzoxazolethiol; 7-Fluoro-2-mercaptobenzoxazole; 7-Fluoro-2(3H)-benzoxazolethione; 2-Mercapto-7-fluorobenzoxazole; 7-Fluoro-1,3-benzoxazole-2-thiol; 7-Fluoro-2-sulfanyl-1,3-benzoxazole; 7-Fluoro-2-oxo-2,3-dihydrobenzoxazole-3-thione; 153403-54-4
EINECS	Contact for details

Quality Control

Our 7-Fluorobenzoxazole-2(3H)-Thione is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment to ensure traceability and compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic).

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.