Description

Acetylamino-(4-Fluoro-Phenyl)-Acetic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecules, particularly due to the presence of the fluorine atom which can dramatically alter a compound's biological activity and metabolic stability. Pharmaceutical research and development organizations need it for the creation of novel active pharmaceutical ingredients (APIs) and agrochemical companies utilize it in the development of new crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), especially in therapeutic areas targeting the central nervous system, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a critical building block for the development of advanced herbicides, fungicides, and insecticides, where the fluorine substituent enhances bioactivity and environmental persistence.
• Material Science Research: Used in the synthesis of specialty polymers, liquid crystals, and organic electronic materials that require fluorinated aromatic components for specific performance characteristics.
• Chemical Biology & Proteomics: Employed as a precursor for designing fluorinated probes, tags, and inhibitors used in studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing tailored compounds for client projects.

Basic Information

Product Name	Acetylamino-(4-Fluoro-Phenyl)-Acetic Acid
CAS No.	153381-37-4
Molecular Formula	C10H10FNO3
Molecular Weight	211.19 g/mol
Synonyms	N-Acetyl-4-fluorophenylglycine; 2-Acetamido-2-(4-fluorophenyl)acetic acid; (4-Fluorophenyl)(acetylamino)acetic acid; 2-(Acetylamino)-2-(4-fluorophenyl)acetic acid; Acetylamino(4-fluorophenyl)acetic acid; N-Acetyl-4-fluoro-DL-phenylglycine; 4-Fluoro-N-acetylphenylglycine; α-Acetamido-4-fluorophenylacetic acid
EINECS	Contact for details

Quality Control

Our Acetylamino-(4-Fluoro-Phenyl)-Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.