Description

4,4,4-Trifluoro-3-(3-Indolyl)Butyric Acid is a high-purity fluorinated indole derivative, a crucial building block in advanced organic synthesis. Its unique structure, featuring both a trifluoromethyl group and an indole moiety, makes it an invaluable intermediate for creating novel compounds with enhanced biological activity and physicochemical properties. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in areas targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Fluorinated Building Block: Serves as a versatile precursor for introducing the CF3 group into more complex molecular architectures in medicinal and materials chemistry.
• Biochemical Research: Employed in the study of enzyme inhibitors and receptor ligands due to its structural similarity to tryptophan metabolites.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for specialized, high-value chemical entities.

Basic Information

Item	Details
Product Name	4,4,4-Trifluoro-3-(3-Indolyl)Butyric Acid
CAS No.	153233-36-4
Molecular Formula	C12H10F3NO2
Molecular Weight	257.21 g/mol
Synonyms	3-(1H-Indol-3-yl)-4,4,4-trifluorobutanoic Acid; 4,4,4-Trifluoro-3-(1H-indol-3-yl)butanoic Acid; 3-(Indol-3-yl)-4,4,4-trifluorobutyric Acid; TFIBA; γ,γ,γ-Trifluoro-β-(3-indolyl)butyric Acid; 4,4,4-Trifluoro-3-indol-3-yl-butyric acid; (RS)-4,4,4-Trifluoro-3-(1H-indol-3-yl)butyric acid
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-3-(3-Indolyl)Butyric Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.