Description

(R)-4-(2-Propenyloxy)-Mandelonitrile is a chiral, non-racemic organic compound featuring a mandelonitrile core with a propenyloxy substituent. This compound serves as a valuable chiral building block and synthetic intermediate in the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of enantiopure drugs, particularly in cardiovascular and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Asymmetric Catalysis: Employed as a ligand precursor or a test substrate in the development of new asymmetric catalytic processes.
• Fine Chemical Production: Serves as a building block for creating complex, high-value specialty chemicals with specific stereochemical requirements.
• Academic & Industrial Research: A critical reagent for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	(R)-4-(2-Propenyloxy)-Mandelonitrile
CAS No.	153225-88-8
Molecular Formula	C11H11NO2
Molecular Weight	189.21 g/mol
Synonyms	(R)-4-(Allyloxy)mandelonitrile; (R)-α-Hydroxy-4-(allyloxy)benzeneacetonitrile; (R)-4-Allyloxymandelonitrile; (R)-2-Hydroxy-2-(4-(prop-2-en-1-yloxy)phenyl)acetonitrile; (R)-O-Allyl-4-hydroxy-mandelonitrile; (R)-4-(Allyloxy)benzaldehyde cyanohydrin; (R)-4-(2-Propen-1-yloxy)mandelonitrile
EINECS	Contact for details

Quality Control

Our (R)-4-(2-Propenyloxy)-Mandelonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.