Description

n-Ethyl-4-Fluoroacetamidobenzovesamicol is a high-purity, specialized organic compound of significant interest in advanced pharmaceutical research and development. Its core value lies in its utility as a key intermediate or reference standard in the synthesis and study of vesicular acetylcholine transporter (VAChT) ligands, which are crucial for neurological research. This product is essential for pharmaceutical companies, contract research organizations (CROs), and academic institutions focused on neurodegenerative disease research, diagnostic agent development, and neuropharmacology.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel compounds targeting the vesicular acetylcholine transporter (VAChT).
• Neurological Research: Used as a reference standard or precursor in the development of positron emission tomography (PET) tracers for imaging cholinergic system integrity.
• Biochemical Tool Compound: Employed in in vitro studies to investigate ligand-receptor interactions and transporter function within the central nervous system.
• Preclinical Development: Serves as a key material in the early-stage discovery and optimization of potential therapeutics for Alzheimer's disease and other cognitive disorders.
• Academic Research: Utilized in university and institutional labs for fundamental studies on neurotransmission and neurochemical pathways.

Basic Information

Product Name	n-Ethyl-4-Fluoroacetamidobenzovesamicol
CAS No.	153216-44-5
Molecular Formula	C21H25FN2O
Molecular Weight	340.44 g/mol
Synonyms	4-Fluoro-N-[2-hydroxy-1,2,2-triphenylethyl]-N-ethylacetamide; Benzovesamicol, 4'-fluoro-N-ethylacetamido derivative; (-)-4-Fluoro-N-ethylacetamidobenzovesamicol; F-AV-133 precursor; VAChT Ligand Intermediate; AV-133 Synthetic Intermediate; FEABV
EINECS	Contact for details

Quality Control

Our n-Ethyl-4-Fluoroacetamidobenzovesamicol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for fine chemical production, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.