Description

(4R,5S,6S,7R)-4,7-Dibenzyl-1,3-Diethyl-5,6-Dihydroxy-1,3-Diazepan-2-One is a high-purity, stereochemically defined diazepanone derivative, serving as a critical chiral building block and synthetic intermediate. Its precise stereochemistry and functional groups make it invaluable for constructing complex molecular architectures with defined three-dimensional orientation. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals requiring specific chiral centers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, especially in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Utilized as a ligand or precursor in catalytic asymmetric reactions to induce high enantioselectivity.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Academic & Institutional Research: Used in universities and R&D institutes for methodological development in organic and synthetic chemistry.
• Process Chemistry Development: Acts as a reference standard or intermediate for scaling up synthetic routes from laboratory to pilot plant scale.

Basic Information

Item	Details
Product Name	(4R,5S,6S,7R)-4,7-Dibenzyl-1,3-Diethyl-5,6-Dihydroxy-1,3-Diazepan-2-One
CAS No.	153181-43-2
Molecular Formula	C24H30N2O3
Molecular Weight	394.51 g/mol
Synonyms	1,3-Diethyl-4,7-dibenzyl-5,6-dihydroxy-1,3-diazepan-2-one; 4,7-Dibenzyl-1,3-diethyl-5,6-dihydroxyperhydro-1,3-diazepin-2-one; (4R,5S,6S,7R)-4,7-Dibenzyl-1,3-diethylhexahydro-5,6-dihydroxy-1H-1,3-diazepin-2-one; Diazepanone derivative, chiral diazepanone intermediate; DBDEHD; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (4R,5S,6S,7R)-4,7-Dibenzyl-1,3-Diethyl-5,6-Dihydroxy-1,3-Diazepan-2-One is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.