Description

2-Chloro-4-Fluoro-5-Iodoanisole is a high-purity, multi-halogenated anisole derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced functional materials used in display technologies, leveraging its halogenated aromatic core.
• Organic Ligand Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new cross-coupling reactions and heterocyclic chemistry.
• Fine Chemical Production: Integral to the multi-step synthesis of complex dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	2-Chloro-4-Fluoro-5-Iodoanisole
CAS No.	153122-59-9
Molecular Formula	C7H5ClFIO
Molecular Weight	285.47 g/mol
Synonyms	1-Chloro-2-fluoro-4-iodo-5-methoxybenzene; 5-Iodo-2-chloro-4-fluoroanisole; Benzene, 1-chloro-2-fluoro-4-iodo-5-methoxy-; 2-Chloro-4-fluoro-1-iodo-5-methoxybenzene; Anisole, 2-chloro-4-fluoro-5-iodo-; 5-Methoxy-2-chloro-4-fluoro-1-iodobenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Fluoro-5-Iodoanisole is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency for your critical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as confirmed by HPLC, GC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.