Description

2-Amino-(6-Amidobiotinyl)Pyridine is a specialized biotin derivative, a key intermediate in the synthesis of advanced bioconjugates and molecular probes. This compound is valued for its ability to introduce a biotin tag onto target molecules, enabling sensitive detection and purification via the strong biotin-streptavidin interaction. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, diagnostic assay production, and life science research for applications such as drug targeting and biomarker labeling.

Application

• Bioconjugation Reagent: Used for the site-specific biotinylation of proteins, antibodies, peptides, and oligonucleotides.
• Diagnostic Assay Development: A critical component in the manufacture of ELISA kits, lateral flow assays, and other immunoassays that rely on streptavidin-biotin chemistry.
• Drug Discovery & Targeting: Facilitates the creation of biotinylated drug candidates or targeting ligands for preclinical research and targeted delivery systems.
• Affinity Purification: Enables the immobilization of biomolecules on streptavidin-coated beads or columns for purification and pull-down assays.
• Molecular Imaging Probes: Serves as a building block for synthesizing probes used in fluorescence microscopy, flow cytometry, and in vivo imaging.
• Chemical Biology Research: Employed in studying protein-protein interactions, cellular trafficking, and signal transduction pathways.

Basic Information

Product Name	2-Amino-(6-Amidobiotinyl)Pyridine
CAS No.	153086-93-2
Molecular Formula	C16H23N5O2S
Molecular Weight	349.46 g/mol
Synonyms	6-[(5-Amino-2-pyridinyl)amino]-6-oxohexanoic acid (side chain of biotin); Biotin-6-amido-pyridine-2-amine; 2-Amino-6-(biotinamido)pyridine; N-(5-Aminopyridin-2-yl)biotinamide; 2-Pyridinamine, 6-[(5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl)amino]-; Biotinylated 2-aminopyridine; Biotin-Py-NH2
EINECS	Contact for details

Quality Control

Our 2-Amino-(6-Amidobiotinyl)Pyridine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. For long-term storage, consider keeping the product desiccated under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.