Description

4-Hydroxy-3-(10-Hydroxydecyl)-5,6-Dimethoxy-2-Methylphenyl β-D-Glucuronide Monosodium Salt is a high-purity, monosodium salt derivative of a complex phenolic glucuronide. This compound is of significant interest for its role as a key metabolite or analytical reference standard in advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in metabolic studies, drug discovery, and the synthesis of specialized bioactive molecules.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the quantification and identification of drug metabolites in pharmacokinetic and bioanalytical studies.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays to study glucuronidation pathways, a critical phase II metabolic process.
• Drug Discovery & Development: Employed in the synthesis and characterization of novel prodrugs or targeted therapeutic agents that utilize glucuronide moieties for enhanced solubility or targeted delivery.
• Analytical Chemistry: Acts as a high-purity calibrant in Liquid Chromatography-Mass Spectrometry (LC-MS) and High-Performance Liquid Chromatography (HPLC) methods for method development and validation.
• Metabolite Synthesis: A crucial intermediate in the chemical synthesis of complex metabolite standards that are not readily available from biological sources.

Basic Information

Product Name	4-Hydroxy-3-(10-Hydroxydecyl)-5,6-Dimethoxy-2-Methylphenyl β-D-Glucuronide Monosodium Salt
CAS No.	153010-37-8
Molecular Formula	C25H39O11Na
Molecular Weight	538.57 g/mol
Synonyms	Monosodium 4-Hydroxy-3-(10-Hydroxydecyl)-5,6-dimethoxy-2-methylphenyl β-D-Glucopyranosiduronate; Sodium (2R,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-[4-hydroxy-3-(10-hydroxydecyl)-5,6-dimethoxy-2-methylphenoxy]oxane-2-carboxylate; β-D-Glucuronide, 4-Hydroxy-3-(10-Hydroxydecyl)-5,6-Dimethoxy-2-Methylphenyl, Monosodium Salt; 153010-37-8; Phenolic Glucuronide Sodium Salt
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3-(10-Hydroxydecyl)-5,6-Dimethoxy-2-Methylphenyl β-D-Glucuronide Monosodium Salt is manufactured under controlled conditions to ensure the highest standards of purity and consistency. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.