Description

3-Pyridinecarbonitrile, 5-Ethynyl- (9Ci) is a high-purity, heterocyclic building block featuring both a nitrile and an ethynyl functional group on a pyridine core. This unique bifunctional structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients, as well as by material scientists exploring new functional polymers and ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of conductive polymers, metal-organic frameworks (MOFs), and other functional materials.
• Chemical Biology Probes: Utilized in click chemistry applications due to the reactive ethynyl group for bioconjugation and labeling.
• Ligand Synthesis: Acts as a precursor for creating sophisticated chelating ligands used in catalysis and metal complexation.
• Academic & Industrial R&D: A versatile building block for exploratory organic synthesis and method development in chemistry laboratories worldwide.

Basic Information

Product Name	3-Pyridinecarbonitrile, 5-Ethynyl- (9Ci)
CAS No.	152803-05-9
Molecular Formula	C8H4N2
Molecular Weight	128.13 g/mol
Synonyms	5-Ethynylnicotinonitrile; 5-Ethynyl-3-cyanopyridine; 3-Cyano-5-ethynylpyridine; 5-Ethynylpyridine-3-carbonitrile; 152803-05-9; 5-Ethynyl-3-pyridinecarbonitrile; Nicotinonitrile, 5-ethynyl-
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarbonitrile, 5-Ethynyl- (9Ci) is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical R&D and production processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for traceable, high-performance chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.