Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl Asn-Otbu is a protected amino acid derivative widely used as a critical building block in solid-phase peptide synthesis (SPPS). This compound is essential for the controlled assembly of complex peptides and proteins, enabling the production of high-purity bioactive molecules. It is primarily needed by research institutions, pharmaceutical development labs, and fine chemical manufacturers focused on peptide-based therapeutics, diagnostics, and biochemical research.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected asparagine derivative for the sequential assembly of peptide chains.
• Pharmaceutical Intermediates: Used in the research and development of peptide-based drugs, including hormones, antibiotics, and enzyme inhibitors.
• Bioconjugation: Acts as a precursor for modifying peptides or proteins with specific functional groups for labeling or cross-linking.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Academic & Industrial Research: A fundamental reagent for studying protein structure, function, and interactions in biochemical laboratories.
• Production of Custom Peptides: Used by CROs and CDMOs for the contract manufacturing of specific peptide sequences for clients.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl Asn-Otbu
CAS No.	152781-25-4
Molecular Formula	C23H26N2O5
Molecular Weight	410.47 g/mol
Synonyms	Fmoc-Asn(OtBu)-OH; Fmoc-L-asparagine(OtBu)-OH; N-α-Fmoc-N-β-tert-Butyloxycarbonyl-L-asparagine; Nα-(9-Fluorenylmethoxycarbonyl)-Nβ-(tert-butoxycarbonyl)-L-asparagine; Fmoc-Asparagine(tBu)-OH; Fmoc-Asn(Boc)-OH (common misnomer); N-Fmoc-N'-Boc-L-asparagine; (2S)-2-[(9H-fluoren-9-ylmethoxy)carbonylamino]-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl Asn-Otbu is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	-15.0° to -20.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.