Description

(R)-n-(Tetrahydrofuran-3-Yl)Benzamide is a high-purity chiral building block and pharmaceutical intermediate of significant interest in modern synthetic chemistry. This compound matters for its role in the development of enantiomerically pure active pharmaceutical ingredients (APIs), where its defined stereochemistry is critical for biological activity and regulatory approval. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly in areas requiring complex, three-dimensional molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and antiviral therapies.
• Asymmetric Synthesis: Used as a building block in catalytic asymmetric reactions to construct complex molecules with high enantiomeric excess.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs due to its tetrahydrofuran moiety.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for API manufacturing under GMP conditions.
• Ligand and Catalyst Preparation: Potential precursor for the synthesis of chiral ligands used in homogeneous catalysis.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(R)-n-(Tetrahydrofuran-3-Yl)Benzamide
CAS No.	152495-79-9
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	(R)-N-(Oxolan-3-yl)benzamide; (R)-3-Benzamidotetrahydrofuran; Benzamide, N-[(3R)-tetrahydro-3-furanyl]-; (R)-Tetrahydrofuran-3-carboxanilide; (3R)-N-Phenyltetrahydrofuran-3-carboxamide; (R)-N-(Tetrahydro-3-furanyl)benzamide; (R)-3-(Benzoylamino)tetrahydrofuran
EINECS	Contact for details

Quality Control

Our (R)-n-(Tetrahydrofuran-3-Yl)Benzamide is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.