Description

1-(Benzyloxy)-2,4-Difluorobenzene is a high-purity fluorinated aromatic ether building block of significant importance in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially those containing difluorophenyl ether motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the benzyloxy-difluorobenzene structure imparts specific biological activity.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronics: Employed in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination for creating complex biaryl structures.
• Chemical Research: A versatile reagent for method development and exploring new fluorination or etherification pathways in academic and industrial laboratories.

Basic Information

Product Name	1-(Benzyloxy)-2,4-Difluorobenzene
CAS No.	152434-86-1
Molecular Formula	C13H10F2O
Molecular Weight	220.22 g/mol
Synonyms	2,4-Difluorophenyl benzyl ether; Benzyl 2,4-difluorophenyl ether; 2,4-Difluoro-1-(phenylmethoxy)benzene; 1-Benzyloxy-2,4-difluorobenzene; (2,4-Difluorophenoxy)methyl]benzene; NSC 339246; BDFB
EINECS	Contact for details

Quality Control

Our 1-(Benzyloxy)-2,4-Difluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.