Description

Benzeneacetic Acid, 3-Fluoro-Alpha,4,5-Trihydroxy- (9Ci) is a fluorinated derivative of mandelic acid, characterized by its unique trifunctional hydroxylated aromatic structure. This compound is valued as a sophisticated synthetic intermediate, enabling the introduction of a fluorinated, hydroxylated phenylacetic acid moiety into target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, where its specific substitution pattern can modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in areas like enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, or plant growth regulators where the fluorine atom enhances bioavailability and stability.
• Chemical Synthesis: Serves as a chiral precursor or a functionalized scaffold in complex organic synthesis and medicinal chemistry programs.
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe for studying enzyme mechanisms involving hydroxy-acid substrates.
• Material Science Research: Investigated as a monomer or functional additive for specialty polymers with specific optical or surface properties.

Basic Information

Product Name	Benzeneacetic Acid, 3-Fluoro-Alpha,4,5-Trihydroxy- (9Ci)
CAS No.	152354-24-0
Molecular Formula	C8H7FO5
Molecular Weight	202.14 g/mol
Synonyms	3-Fluoro-α,4,5-trihydroxybenzeneacetic acid; 2-(3-Fluoro-4,5-dihydroxyphenyl)-2-hydroxyacetic acid; 3-Fluoromandelic acid, 4,5-dihydroxy-; 3-Fluoro-4,5-dihydroxymandelic acid; (2R/S)-2-Hydroxy-2-(3-fluoro-4,5-dihydroxyphenyl)acetic acid; α-Hydroxy-3-fluoro-4,5-dihydroxybenzeneacetic acid; 3-Fluoro-α,4,5-trihydroxybenzenecetic acid
EINECS	Contact for details

Quality Control

Our production of Benzeneacetic Acid, 3-Fluoro-Alpha,4,5-Trihydroxy- (9Ci) adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development and scale-up projects with material produced under a quality management system designed to meet the exacting standards of research and pre-clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.