Description

(S)3-(9H-Fluoren-9-Ylmethoxycarbonylamino)-Succinamic Acid Methyl Ester is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. Its primary value lies in enabling the controlled synthesis of complex peptides and other bioactive molecules, ensuring high coupling efficiency and stereochemical integrity. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries, particularly in the development of novel therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected intermediate for the sequential assembly of peptides, especially those requiring specific side-chain modifications.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based drug candidates, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, polymers, or solid surfaces in diagnostic and drug delivery system development.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for high-throughput screening in drug discovery programs.
• Fine Chemical Synthesis: Acts as a chiral synthon for the preparation of non-peptide compounds where the (S)-succinamic acid scaffold is required.
• Academic Research: A valuable reagent for studying peptide structure-activity relationships and developing new synthetic methodologies.

Basic Information

Item	Details
Product Name	(S)3-(9H-Fluoren-9-Ylmethoxycarbonylamino)-Succinamic Acid Methyl Ester
CAS No.	152338-32-4
Molecular Formula	C24H22N2O6
Molecular Weight	434.44 g/mol
Synonyms	Fmoc-Asp(OtBu)-OH methyl ester; Fmoc-L-Aspartic acid 4-tert-butyl ester methyl ester; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)succinic acid 4-tert-butyl 1-methyl ester; Fmoc-Asp(OtBu)-OMe; Nα-Fmoc-L-aspartic acid β-tert-butyl ester α-methyl ester; N-Fmoc-L-aspartic acid 4-tert-butyl ester 1-methyl ester; Fmoc-Asp(OtBu)-Me; Protected L-Aspartic Acid Derivative
EINECS	Contact for details

Quality Control

Our (S)3-(9H-Fluoren-9-Ylmethoxycarbonylamino)-Succinamic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and cGMP-grade standards for pharmaceutical applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (S-enantiomer)
Loss on Drying	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.