Description

M Protein Epitope Of Group A Streptococci CAS NO 152044-86-5 is a defined peptide sequence representing a key antigenic region of the M protein from *Streptococcus pyogenes*. This high-purity synthetic epitope is critical for research and diagnostic applications focused on streptococcal immunity and pathogenesis. It is primarily utilized by biotechnology firms, academic research institutions, and diagnostic kit manufacturers for vaccine development, immunological assays, and antibody specificity studies.

Application

• Immunological Research: Used as a specific antigen to study host immune responses, antibody production, and T-cell reactivity to Group A Streptococci (GAS).
• Vaccine Development: Serves as a key component in the research and preclinical evaluation of candidate vaccines targeting streptococcal M protein.
• Diagnostic Assays: Employed as a coating antigen or detection target in ELISA, Western Blot, and other immunoassays for detecting GAS-specific antibodies in patient sera.
• Antibody Production & Characterization: Acts as an immunogen for generating monoclonal or polyclonal antibodies with defined specificity for M protein epitopes.
• Structural Biology Studies: Used in epitope mapping, binding affinity studies, and structural analysis of antigen-antibody interactions.
• Quality Control Reference: Functions as a reference standard in the quality control of diagnostic kits and immunological reagents targeting GAS.

Basic Information

Product Name	M Protein Epitope Of Group A Streptococci
CAS No.	152044-86-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Streptococcal M Protein Epitope; GAS M Protein Peptide; M Protein Antigenic Peptide; *Streptococcus pyogenes* M Protein Epitope; Streptococcal Epitope; M Protein Fragment; Group A Streptococcal Antigen; Synthetic M Protein Peptide
EINECS	Contact for details

Quality Control

Our M Protein Epitope is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by HPLC and identity confirmation by mass spectrometry. A Certificate of Analysis (COA) detailing purity, sequence verification, and endotoxin levels is provided with every shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, consider aliquoting to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Amino Acid Sequence	Verified
Solubility	Soluble in water or appropriate aqueous buffers
Endotoxin Level	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.