Description

Ac-Asp-Arg-Gly-Asp-Ser-Oh is a synthetic peptide sequence, also known as Ac-DRGD-OH, which is a key motif in cell adhesion and signaling. This compound is of significant interest for its role in mimicking the integrin-binding RGD sequence found in extracellular matrix proteins like fibronectin. It is primarily utilized by researchers and developers in the fields of biomedical research, pharmaceutical development, and biomaterials science for studying cell-surface interactions, designing drug delivery systems, and creating bioactive coatings.

Application

• Biomedical Research: As a critical tool for studying integrin-mediated cell adhesion, migration, and signaling pathways in vitro.
• Drug Discovery & Development: Serving as a targeting ligand or a competitive inhibitor in the design of novel therapeutics for cancer, thrombosis, and osteoporosis.
• Biomaterials & Tissue Engineering: Functionalizing surfaces of implants, scaffolds, and medical devices to promote specific cellular attachment and tissue integration.
• Diagnostic Assay Development: Used in the development of assays to screen for compounds that modulate integrin activity.
• Peptide Synthesis & Conjugation: Acting as a building block or a functional handle for the synthesis of more complex peptide-based constructs and bioconjugates.

Basic Information

Product Name	Ac-Asp-Arg-Gly-Asp-Ser-Oh
CAS No.	151997-55-6
Molecular Formula	C23H37N9O12
Molecular Weight	607.59 g/mol
Synonyms	Ac-DRGD-OH; Ac-Asp-Arg-Gly-Asp-Ser; N-Acetyl-Asp-Arg-Gly-Asp-Ser; Acetylated DRGD Peptide; RGD Peptide Derivative; Ac-DRGD; N-Acetyl-L-aspartyl-L-arginylglycyl-L-aspartyl-L-serine; Integrin-binding peptide motif
EINECS	Contact for details

Quality Control

Our Ac-Asp-Arg-Gly-Asp-Ser-Oh is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot is characterized by advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment to guarantee compliance with your specific research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.