Description

Ac2-26 CAS NO 151988-33-9 is a synthetic peptide fragment derived from the N-terminus of Annexin A1, known for its potent anti-inflammatory and pro-resolving properties. This compound is a critical research tool for investigating the formyl peptide receptor (FPR) signaling pathway and its role in modulating immune responses. It is essential for scientists and developers in the fields of immunology, pharmacology, and drug discovery, particularly for studying inflammation-related diseases and developing novel therapeutic agents.

Application

• Biomedical Research: Used as a key reagent to study the mechanisms of inflammation resolution and the biological functions of Annexin A1.
• Drug Discovery & Development: Serves as a reference standard and lead compound for developing new anti-inflammatory and immunomodulatory drugs targeting FPR receptors.
• In Vitro & In Vivo Studies: Applied in cell-based assays and animal models to evaluate anti-inflammatory efficacy and signal transduction pathways.
• Academic Research: Fundamental tool for universities and research institutes exploring innate immunity, leukocyte biology, and chronic inflammatory conditions.
• Pharmaceutical QC: Potential use as a standard for quality control in the development of peptide-based therapeutics.

Basic Information

Product Name	Ac2-26
CAS No.	151988-33-9
Molecular Formula	C130H204N38O41
Molecular Weight	2843.2 g/mol
Synonyms	Annexin A1 (2-26) peptide; Ac-AMVSEFLKQAWIENEEQEYVQTVK-NH2; N-Acetyl-Annexin A1 (2-26) amide; FPR2/ALX agonist peptide; Anti-inflammatory peptide Ac2-26; Annexin I N-terminal peptide; ANXA1-derived peptide; Peptide Ac2-26
EINECS	Contact for details

Quality Control

Our Ac2-26 is manufactured under strict quality management systems to ensure the highest standards of purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical characterization, including HPLC, MS, and amino acid analysis. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are provided with every shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the peptide desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.