Description

Technetium Tc 99M 6-(4-Thioureabenzyl)-3,3,9,9-Tetramethyl-4,8-Diazaundecane-Phenylalanine(1)-Octreotide is a sophisticated radiopharmaceutical precursor designed for the preparation of diagnostic imaging agents. This compound is critical for the precise and reliable radiolabeling of octreotide analogs, enabling high-contrast visualization of somatostatin receptor-positive tumors. It is an essential material for radiopharmacies, clinical research organizations, and manufacturers of diagnostic kits targeting neuroendocrine tumors and other oncological conditions.

Application

• Primary Use: Radiolabeling precursor for the synthesis of [99mTc]Tc-TOC and related octreotide-based diagnostic imaging agents.
• Oncological Diagnostics: Used in Single Photon Emission Computed Tomography (SPECT) for the detection, localization, and staging of neuroendocrine tumors (NETs), including carcinoid tumors, pheochromocytomas, and paragangliomas.
• Clinical Research: Serves as a key reagent in the development and validation of novel somatostatin receptor-targeted radiopharmaceuticals.
• Radiopharmacy Kits: A critical component in the formulation of cold kits for the convenient, on-site preparation of patient-ready diagnostic doses.
• Therapeutic Companion Diagnostics: Aids in patient selection and monitoring for peptide receptor radionuclide therapy (PRRT).

Basic Information

Item	Details
Product Name	Technetium Tc 99M 6-(4-Thioureabenzyl)-3,3,9,9-Tetramethyl-4,8-Diazaundecane-Phenylalanine(1)-Octreotide
CAS No.	151956-25-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Technetium-99m TOC precursor; [99mTc]Tc-TOC Kit Intermediate; 6-(4-Thioureabenzyl)-3,3,9,9-tetramethyl-4,8-diazaundecane-2,10-dione dioxime-Phe(1)-Tyr(3)-octreotide (Tc-99m); HYNIC-TOC (for Tc-99m labeling); Tc-99m EDDA/HYNIC-TOC; Tc-99m-Tektrotyd precursor; Somatostatin analog Tc-99m labeling agent
EINECS	Contact for details

Quality Control

This high-purity precursor is manufactured under strict GMP-compliant conditions to ensure batch-to-batch consistency and reliability for clinical use. Every lot is subjected to rigorous analytical testing, including HPLC for radiochemical purity and identity confirmation, to meet exacting pharmaceutical standards. A comprehensive Certificate of Analysis (COA), detailing all release specifications, is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. Due to its sensitivity, the product should be handled under an inert atmosphere when opened to prevent oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Radiochemical Purity (Post-labeling)	≥ 90.0% (as per kit instructions)
Specific Activity	Contact for details
Residual Solvents (GC)	Complies with ICH guidelines
Bacterial Endotoxins	< 175 EU/vial
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.