Description

Calcobutrol is a high-purity, specialized chemical compound used primarily as a key intermediate in advanced pharmaceutical synthesis. Its precise molecular structure makes it a critical building block for developing novel contrast agents and diagnostic imaging compounds. This product is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical suppliers operating in the global life sciences sector.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of next-generation gadolinium-based contrast agents (GBCAs) for Magnetic Resonance Imaging (MRI).
• Diagnostic Agent Research: Serves as a scaffold molecule in the development of targeted imaging probes for enhanced diagnostic accuracy.
• Fine Chemical Synthesis: Used in multi-step organic synthesis for creating complex, high-value molecules with specific chelating properties.
• Academic & Industrial R&D: Employed in chemical research to study structure-activity relationships (SAR) and develop new macrocyclic compounds.

Basic Information

Product Name	Calcobutrol
CAS No.	151878-23-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Gadobutrol precursor; Butrol intermediate; 10-(2,3-Dihydroxy-1-(hydroxymethyl)propyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid derivative; Macrocyclic triamine derivative; DO3A-butrol; Gadolinium chelator intermediate; Contrast agent intermediate
EINECS	Contact for details

Quality Control

Our Calcobutrol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.