Description

3-Hydroxy-5-Estrane-17-Carbonitrile is a high-purity steroidal nitrile derivative, serving as a critical advanced intermediate in organic synthesis. Its value lies in providing a versatile chemical scaffold for the development of novel pharmaceutical compounds and research chemicals. This product is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries, particularly those focused on steroid chemistry and hormone-related therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of new chemical entities.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Biochemical Research: Utilized in studies investigating steroid hormone pathways, receptor binding, and enzyme inhibition.
• Fine Chemical Synthesis: An intermediate for producing specialized, high-value chemicals used in various advanced research applications.

Basic Information

Product Name	3-Hydroxy-5-Estrane-17-Carbonitrile
CAS No.	151774-83-3
Molecular Formula	C19H27NO
Molecular Weight	285.43 g/mol
Synonyms	3-Hydroxy-5-estrane-17-carbonitrile; 17-Cyano-5-estran-3-ol; 5-Estran-3-ol-17-carbonitrile; 3-Hydroxy-17-cyano-5-estrane; 17-Cyano-3-hydroxy-5-estrane; Estrane-17-carbonitrile, 3-hydroxy-; 3-Hydroxyestra-5-ene-17-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-5-Estrane-17-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods (IR, NMR), to ensure it meets exacting standards for research and synthesis. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.