Description

Capromab is a monoclonal antibody-based diagnostic agent, specifically a murine IgG1 antibody, with the CAS registry number 151763-64-3. This compound is of significant value in the field of oncology for the targeted detection and imaging of prostate-specific membrane antigen (PSMA). It is primarily needed by pharmaceutical manufacturers, clinical research organizations, and diagnostic imaging centers for the development and application of advanced cancer diagnostic and therapeutic strategies.

Application

• Primary use as a diagnostic imaging agent for the detection and staging of prostate cancer.
• Component in the formulation of ProstaScint®, an FDA-approved radioimmunoscintigraphic imaging agent.
• Used in clinical research to study the expression and localization of PSMA in various cancers.
• Potential applications in the development of targeted radiotherapy (radioimmunotherapy) for prostate cancer.
• Tool for biochemical and immunological assays requiring specific anti-PSMA antibody binding.
• Reference standard in the quality control and validation of PSMA-targeting diagnostic kits.

Basic Information

Product Name	Capromab
CAS No.	151763-64-3
Molecular Formula	Contact for details
Molecular Weight	Approx. 150 kDa (Monoclonal Antibody)
Synonyms	Capromab Pendent; 7E11-C5.3; Anti-PSMA Monoclonal Antibody (7E11-C5.3); Monoclonal Antibody 7E11-C5.3; Prostate-Specific Membrane Antigen-Specific Antibody; ProstaScint Antibody; CYT-356; Indium In 111 Capromab Pendent Precursor
EINECS	Contact for details

Quality Control

Our Capromab is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including SDS-PAGE for purity, ELISA for immunoreactivity, and endotoxin testing, to ensure it meets the high standards required for diagnostic and research applications. Certificates of Analysis (COA) detailing identity, purity, potency, and sterility are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be handled aseptically and stored at 2-8°C for short-term use. The product is hygroscopic (moisture-sensitive) and light-sensitive; avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE/ELISA)	Complies
Purity (SDS-PAGE)	≥ 95% (Reduced & Non-reduced)
Protein Content (UV Absorbance)	≥ 1.0 mg/vial
Immunoreactivity (ELISA)	≥ 80% binding to PSMA
Endotoxin (LAL)	< 10 EU/mg
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.