Description

Lcmv Gp33–41 is a synthetic peptide antigen derived from the glycoprotein of the Lymphocytic Choriomeningitis Virus (LCMV). This high-purity biochemical is critical for immunological research and diagnostic assay development, specifically targeting the GP33-41 epitope. It is an essential reagent for scientists in virology, immunology, and vaccine research studying T-cell responses, immune memory, and viral pathogenesis mechanisms.

Application

• Immunological Research: Used as a specific antigen to stimulate and detect CD8+ T-cell responses in studies of antiviral immunity.
• Vaccine Development: Serves as a key component in epitope-specific vaccine research and efficacy testing for LCMV and related arenaviruses.
• Diagnostic Assays: Employed in the development and calibration of ELISpot, intracellular cytokine staining (ICS), and tetramer staining assays to quantify antigen-specific T cells.
• T-Cell Receptor (TCR) Studies: Essential for characterizing TCR affinity, specificity, and signaling in transgenic mouse models and humanized systems.
• Infectious Disease Modeling: A fundamental tool in murine models of chronic viral infection and immune exhaustion.
• Quality Control (QC) for Therapeutics: Used as a reference standard in the QC of immunotherapies and vaccines targeting LCMV-derived epitopes.

Basic Information

Product Name	Lcmv Gp33–41
CAS No.	151705-84-9
Molecular Formula	C44H72N14O12
Molecular Weight	981.1 g/mol
Synonyms	LCMV Glycoprotein (33-41); LCMV GP33-41; H-2Db-restricted LCMV epitope; KAVYNFATM; GP33 Peptide; LCMV epitope GP33; Lymphocytic choriomeningitis virus glycoprotein residues 33-41; Antigenic Peptide GP33-41
EINECS	Contact for details

Quality Control

Every batch of Lcmv Gp33–41 is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC and MS, to ensure high purity and correct sequence verification. Certificates of Analysis (COA) detailing purity, identity, and endotoxin levels are provided with each shipment to support your research compliance and reproducibility requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms
Peptide Content	≥ 70%
Solubility	Soluble in water or DMSO
Endotoxin Level	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.