Description

4-(n-Maleimido)Benzyl-A-Trimethylammonium Iodide is a heterobifunctional crosslinking reagent featuring a maleimide group and a quaternary ammonium moiety. This compound is specifically engineered for the covalent conjugation of biomolecules, enabling the stable modification of proteins, peptides, and other nucleophilic targets. It is an essential tool for researchers and manufacturers in the fields of bioconjugation, diagnostic assay development, and advanced material science, where precise and stable chemical linkages are required.

Application

• Bioconjugation Reagent: For covalent coupling of thiol-containing molecules (e.g., antibodies, peptides) to surfaces or other molecules via the maleimide group.
• Diagnostic Kit Development: Used in the preparation of enzyme-labeled antibodies or antigens for ELISA and lateral flow assays.
• Polymer and Material Modification: Introducing permanent cationic charges or reactive handles onto polymer backbones, membranes, or nanoparticles.
• Affinity Chromatography Ligand Synthesis: Immobilization of ligands onto solid supports for purification processes.
• Protein and Antibody-Drug Conjugate (ADC) Research: As a building block or linker in the development of novel therapeutic conjugates.
• Surface Functionalization: Creating reactive or charged interfaces on biosensors, chips, and other analytical devices.

Basic Information

Product Name	4-(n-Maleimido)Benzyl-A-Trimethylammonium Iodide
CAS No.	151649-48-8
Molecular Formula	C15H19IN2O2
Molecular Weight	410.23 g/mol
Synonyms	4-(N-Maleimidomethyl)benzyltrimethylammonium Iodide; N-(4-Trimethylammoniobenzyl)maleimide Iodide; Maleimidobenzyltrimethylammonium Iodide; MBTA Iodide; QBT Iodide; 4-Maleimidobenzyltrimethylammonium Iodide; 1-[4-(Trimethylammonio)benzyl]pyrrole-2,5-dione Iodide
EINECS	Contact for details

Quality Control

Our 4-(n-Maleimido)Benzyl-A-Trimethylammonium Iodide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and elemental analysis, to ensure it meets the high standards required for research and bioconjugation applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMF, DMSO, water, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.