Description

5-o-Desmethyl Omeprazole is a key pharmaceutical intermediate and metabolite of the widely used proton pump inhibitor, Omeprazole. This compound is of significant importance for research and development in the pharmaceutical industry, particularly for metabolic studies, impurity profiling, and the synthesis of novel therapeutic agents. It is primarily required by pharmaceutical manufacturers, analytical laboratories, and research institutions engaged in drug development, quality control, and bioanalytical studies.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced Omeprazole derivatives and related proton pump inhibitors.
• Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of Omeprazole metabolites in bioanalytical studies.
• Impurity Profiling: Essential for the analysis and control of process-related impurities in Omeprazole API (Active Pharmaceutical Ingredient) manufacturing to meet pharmacopeial standards.
• Metabolic Research: Serves as a standard in pharmacokinetic and pharmacodynamic studies to understand the metabolic pathways of Omeprazole.
• Analytical Method Development: Utilized in HPLC, LC-MS, and other chromatographic methods for calibration and validation purposes.

Basic Information

Product Name	5-o-Desmethyl Omeprazole
CAS No.	151602-49-2
Molecular Formula	C16H18N3O3S
Molecular Weight	332.40 g/mol
Synonyms	5-Hydroxy Omeprazole; Omeprazole 5-O-Desmethyl; 5-ODM Omeprazole; 6-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole; 5-O-Desmethyl Omeprazole; 5-Desmethoxy Omeprazole; 5-Hydroxy-6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
EINECS	Contact for details

Quality Control

Our 5-o-Desmethyl Omeprazole is manufactured under strict quality control protocols to ensure high purity and consistency suitable for pharmaceutical research and development. Each batch is tested against rigorous in-house specifications, which typically include identity confirmation, assay, and related substance analysis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.