Description

Boc-S-(2-(4-Pyridyl)Ethyl)-L-Cysteine is a protected amino acid derivative featuring a Boc (tert-butoxycarbonyl) group on the amine and a pyridylethyl moiety on the cysteine sulfur. This compound is a critical building block in peptide synthesis and medicinal chemistry, enabling the controlled introduction of a thiol group with a specific, modifiable heterocyclic side chain. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for developing novel therapeutic peptides, bioconjugates, and chemical probes.

Application

• Peptide Synthesis: Serves as a key intermediate for incorporating a protected cysteine residue with a pyridyl-based functional handle into custom peptide sequences.
• Bioconjugation & Linker Chemistry: The pyridylethyl-protected thiol group is valuable for creating disulfide linkages or for post-synthetic modification in antibody-drug conjugates (ADCs) and protein labeling.
• Medicinal Chemistry Research: Used in the design and synthesis of peptide-based drug candidates, enzyme inhibitors, and receptor ligands targeting various diseases.
• Chemical Biology Probes: Employed to create tools for studying protein function, protein-protein interactions, and cellular pathways via site-specific modification.
• Protecting Group Strategy: The Boc group allows for orthogonal deprotection in complex multi-step syntheses, providing flexibility in synthetic routes.

Basic Information

Product Name	Boc-S-(2-(4-Pyridyl)Ethyl)-L-Cysteine
CAS No.	151545-15-2
Molecular Formula	C15H22N2O4S
Molecular Weight	326.41 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-S-[2-(4-pyridinyl)ethyl]-L-cysteine; Boc-Cys(4-Pyridinylethyl)-OH; (S)-2-((tert-Butoxycarbonyl)amino)-3-((2-(pyridin-4-yl)ethyl)thio)propanoic acid; N-Boc-S-(2-(4-Pyridyl)ethyl)cysteine; Boc-L-Cysteine(S-2-(4-pyridyl)ethyl); tert-Butyloxycarbonyl-S-(2-(4-pyridyl)ethyl)-L-cysteine; Nα-Boc-S-(4-pyridin-2-ylethyl)-L-cysteine
EINECS	Contact for details

Quality Control

Our Boc-S-(2-(4-Pyridyl)Ethyl)-L-Cysteine is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.