Description

Benzamide, n-Bicyclo[1.1.1]pent-1-yl- is a specialized bicyclic amide derivative of significant interest in advanced organic synthesis. This compound matters as a unique and valuable building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, where its rigid [1.1.1]propellane core offers distinct spatial and electronic properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its unique bicyclic structure for enhanced biological activity.
• Material Science: Acts as a monomer or cross-linking agent in the creation of polymers with specific thermal or mechanical properties.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe: Utilized as a scaffold for developing molecular probes to study enzyme function and protein-protein interactions.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including strain-release and cross-coupling reactions.

Basic Information

Product Name	Benzamide, n-Bicyclo[1.1.1]pent-1-yl-
CAS No.	151361-59-0
Molecular Formula	C12H13NO
Molecular Weight	187.24 g/mol
Synonyms	N-([1.1.1]Propellane-1-yl)benzamide; 1-Benzamido[1.1.1]propellane; Bicyclo[1.1.1]pentane-1-carboxamide, N-phenyl-; Benzamide, N-(bicyclo[1.1.1]pent-1-yl)-; [1.1.1]Propellanylbenzamide; 1-Aminobicyclo[1.1.1]pentane benzamide derivative
EINECS	Contact for details

Quality Control

Our Benzamide, n-Bicyclo[1.1.1]pent-1-yl- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.