Description

1,2-Dichloro-4-(Trifluoromethoxy)Benzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethoxy substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D and process development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for the synthesis of specialty monomers, ligands, and liquid crystals, contributing to the development of novel polymers and functional materials.
• Chemical Intermediate: Employed in further functionalization reactions, such as cross-coupling (Suzuki, Buchwald-Hartwig), to introduce complex aromatic systems into target molecules.

Basic Information

Product Name	1,2-Dichloro-4-(Trifluoromethoxy)Benzene
CAS No.	151276-10-7
Molecular Formula	C7H3Cl2F3O
Molecular Weight	231.00 g/mol
Synonyms	3,4-Dichloro-1-(trifluoromethoxy)benzene; 1,2-Dichloro-4-(trifluoromethoxy)benzene; 4-(Trifluoromethoxy)-1,2-dichlorobenzene; Benzene, 1,2-dichloro-4-(trifluoromethoxy)-; 3,4-Dichloro-alpha,alpha,α-trifluoroanisole
EINECS	Contact for details

Quality Control

Our 1,2-Dichloro-4-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including GC/HPLC for assay and impurity profiling, to meet the stringent requirements of research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Purity (GC Area %)	≥ 99.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.