Description

Boc-L-2-Amino-4-Bromo-4-Pentenoic Acid is a protected, non-proteinogenic amino acid derivative featuring a reactive bromoalkene side chain. This compound is a crucial chiral building block in organic synthesis, enabling the precise introduction of functionalized amino acid motifs into complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of peptide mimetics, protease inhibitors, and other biologically active molecules.
• Peptidomimetic Research: Used to incorporate constrained or functionalized amino acid residues into peptide backbones to modulate stability, activity, and bioavailability.
• Chemical Biology Probes: The reactive bromoalkene group allows for further functionalization via cross-coupling reactions (e.g., Suzuki, Heck) for labeling or bioconjugation applications.
• Agrochemical Synthesis: Employed as a building block for creating novel herbicides, fungicides, or plant growth regulators with specific chiral centers.
• Material Science: Potential use in the synthesis of functional polymers and dendrimers with tailored properties.
• Academic & R&D: A valuable reagent for methodological development in asymmetric synthesis and organocatalysis studies.

Basic Information

Product Name	Boc-L-2-Amino-4-Bromo-4-Pentenoic Acid
CAS No.	151215-34-8
Molecular Formula	C₁₀H₁₆BrNO₄
Molecular Weight	294.14 g/mol
Synonyms	(2S)-2-[(tert-Butoxycarbonyl)amino]-4-bromopent-4-enoic acid; Boc-L-4-Bromopent-4-enoylalanine; N-(tert-Butoxycarbonyl)-4-bromo-L-homoallylglycine; Boc-4-BroPen-OH; Boc-L-2-Amino-4-bromopent-4-enoic acid; N-Boc-4-bromo-L-homoallylglycine; (S)-2-((tert-Butoxycarbonyl)amino)-4-bromopent-4-enoic acid
EINECS	Contact for details

Quality Control

Our Boc-L-2-Amino-4-Bromo-4-Pentenoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.