Description

Serine, 2-(Fluoromethyl)-, Methyl Ester (9Ci) is a fluorinated derivative of the amino acid serine, serving as a sophisticated building block in advanced organic synthesis. This compound is valued for its ability to introduce fluorine atoms and serine-like motifs into target molecules, a critical strategy for modulating the physicochemical and biological properties of pharmaceuticals and agrochemicals. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated amino acid analogs and peptide mimetics in drug discovery programs.
• Medicinal Chemistry Research: Used to explore structure-activity relationships (SAR) by introducing fluorine to enhance metabolic stability, bioavailability, or binding affinity of lead compounds.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, or plant growth regulators with improved efficacy.
• Biochemical Probe Development: Utilized in the creation of labeled or modified peptides and proteins for biochemical and biophysical studies.
• Specialty Chemical Manufacturing: Acts as a fluorinated synthon for producing advanced materials, liquid crystals, or specialty polymers.

Basic Information

Product Name	Serine, 2-(Fluoromethyl)-, Methyl Ester (9Ci)
CAS No.	151028-30-7
Molecular Formula	C5H10FNO3
Molecular Weight	151.14 g/mol
Synonyms	Methyl 2-(fluoromethyl)serinate; L-Serine, 2-(fluoromethyl)-, methyl ester; (2S)-2-Amino-3-(fluoromethoxy)propanoic acid methyl ester; 2-(Fluoromethyl)serine methyl ester; Fluoromethyl serine methyl ester; Methyl (2S)-2-amino-3-(fluoromethoxy)propanoate; 151028-30-7; Methyl O-(fluoromethyl)-L-serinate
EINECS	Contact for details

Quality Control

Our Serine, 2-(Fluoromethyl)-, Methyl Ester (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR, and MS for structural confirmation, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, enantiomeric excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.